Blar i forfatter "Pang, Zhigang"
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Differential profile of protumor immunological factors between the tumor site and the tumor-free site – predictive potential of IL-8 and COX2 for colorectal cancer and metastasis
Cui, Guanglin; Yuan, Aping; Pang, Zhigang; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-05)To study the role of host immune surveillance in the initiation and progression of colorectal cancer (CRC), a set of protumor immunological factors was determined by quantitative real-time PCR (q-PCR) between the primary tumor and the adjacent tumor-free site tissues in 63 patients with colorectal neoplasms. Results showed that expression levels of interleukin (IL)-1β, IL-6, IL-8, IL-17A, IL-23, and ... -
The presentation and regulation of the IL-8 network in the epithelial cancer stem-like cell niche in patients with colorectal cancer
Cui, Guanglin; Li, Gui; Pang, Zhigang; Florholmen, Jon; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-07)Background: Accumulative evidence suggests that the biological behavior of cancer stem-like cells (CSCs) is regulated by their surrounding niche, in which cytokines function as one of the main mediators for the interaction between CSCs and their microenvironment in the colorectal cancer (CRC).<p> <p>Methods: We characterized the presentation of CSCs and the interleukin (IL)− 8 network in the ...